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6 Years or OlderInitial dose0.7 mg/kg orally once a dayup to 50 mg total)

COZAAR25 mgare whiteovalfilm-coated tablets with code 951 on one sideCOZAAR50 mgare whiteovalfilm-coated tablets with code 952 on one side and scored on the otherCOZAAR100 mgare whiteteardrop-shapedfilm-coated tablets with code 960 on one side.

Losartan potassium is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01It is freely soluble in watersoluble in alcoholsand slightly soluble in common organic solventssuch as acetonitrile and methyl ethyl ketoneOxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

The usual starting dose is 50 mg once dailyThe dose may be increased to 100 mg once daily based on blood pressure response from one month onwards after initiation of therapyLosartan may be administered with other antihypertensive agentse.gdiureticscalcium channel blockersalphaor beta-blockersand centrally acting agentssee sections 4.34.44.5and 5.1as well as with insulin and other commonly used hypoglycemic agentse.gsulfonylureasglitazones and glucosidase inhibitors

Tell your doctor if your condition does not improve or if it worsensfor exampleyour blood pressure readings increase

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cozaar contains the active ingredient losartan, which works by preventing blood vessels in the body from constricting and blocking blood flow to the heart and other vital organs.