The most common side effects of indinavir include gastrointestinal disturbances abdominal pain, diarrhea, nausea, vomiting general malaise and fatigue.

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Patients with hemophiliaThere have been reports of spontaneous bleeding in patients with hemophilia A and B treated with protease inhibitorsIn some patientsadditional factor VIII was requiredIn many of the reported casestreatment with protease inhibitors was continued or restartedA causal relationship between protease inhibitor therapy and these episodes has not been establishedSee ADVERSE REACTIONSPost-Marketing Experience

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3Skinhair and nails Some indinavir users have reported thinner hair or temporary loss of hairDry skindry or cracked lipsand ingrown toenails have also been reported by indinavir usersThese symptoms are sometimes referred to as ectodermal dysplasiaFor more information about options to help manage this please see CATIE's A Practical Guide to HIV Drug Side Effects

The chemical name for indinavir sulfate is1(1S,2R5(S2,3,5-trideoxy-N2,3-dihydro-2-hydroxy-1Hinden-

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